In GLP, what does a certificate of analysis (COA) typically verify?

• A. Conformity with material specifications and SOPs
• B. Pricing and delivery standards
• C. Employee credentials
• D. Weather conditions during shipment

Answer: (A)

A certificate of analysis in GLP is a document that shows a material or product has been tested and meets the defined specifications and the lab’s SOPs. It is issued by the supplier or testing lab and usually lists the material identity, batch/lot number, analytical methods used, test results, acceptance criteria, and an approval signature. This makes it a trusted record that the material conforms to the required quality and procedural standards, providing traceability and confidence for the study. It isn’t about pricing or delivery standards, employee credentials, or weather conditions during shipment, which are outside the scope of the COA.